FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione ID (Ontology) GO:0019243 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.[ PubMed:2198020 ]
Also Known As "methylglyoxal catabolism to D-lactate via S-lactoyl-glutathione"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione (all annotations which use CV term, excluding "NOT" statements)       2
     involved_in | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione       2
Spanning Tree (Parents/Children)
Only view relationship: 
lactate metabolic process________
methylglyoxal catabolic process__|
                                 methylglyoxal catabolic process to lactate
                                  |__methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione  2 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a methylglyoxal catabolic process to lactate
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "D-lactate biosynthesis from methylglyoxal" BROAD
    "D-lactate biosynthetic process from methylglyoxal" BROAD
    "glyoxalase system" RELATED
    "methylglyoxal breakdown to D-lactate" BROAD
    "methylglyoxal catabolism to D-lactate via S-lactoyl-glutathione" EXACT
    "methylglyoxal degradation to D-lactate" BROAD
    "methylglyoxal detoxification" RELATED
Secondary IDs
hide External Crossreferences & Linkouts
MetaCyc:PWY-5386