FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term isopentenyl diphosphate biosynthetic process, mevalonate pathway ID (Ontology) GO:0019287 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.
Also Known As "Ac-MVA pathway" ; "acetate-mevalonate pathway" ; "isopentenyl diphosphate anabolism, mevalonate pathway" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       3
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 isopentenyl diphosphate biosynthetic process, mevalonate pathway (all annotations which use CV term, excluding "NOT" statements)       3
     involved_in | isopentenyl diphosphate biosynthetic process, mevalonate pathway       3
Spanning Tree (Parents/Children)
Only view relationship: 
acyl-CoA metabolic process
 |__acetyl-CoA metabolic process__________________
isoprenoid biosynthetic process                   |
 |__isopentenyl diphosphate biosynthetic process__|
phospholipid biosynthetic process                 |
 |__isopentenyl diphosphate biosynthetic process__|
isopentenyl diphosphate metabolic process         |
 |__isopentenyl diphosphate biosynthetic process__|
                                                  isopentenyl diphosphate biosynthetic process, mevalonate pathway  3 rec.
                                                   |__isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process
                                                   |__regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway
                                                       |__negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway
                                                       |__positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a acetyl-CoA metabolic process
isopentenyl diphosphate biosynthetic process
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "Ac-MVA pathway" EXACT[ PubMed:14517367 ]
    "acetate-mevalonate pathway" EXACT[ PubMed:14517367 ]
    "isopentenyl diphosphate anabolism, mevalonate pathway" EXACT
    "isopentenyl diphosphate biosynthetic process via mevalonate" EXACT
    "isopentenyl diphosphate formation, mevalonate pathway" EXACT
    "isopentenyl diphosphate synthesis, mevalonate pathway" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
MetaCyc:PWY-922