FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term isopentenyl diphosphate biosynthetic process, mevalonate pathway ID (Ontology) GO:0019287 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.
Also Known As "Ac-MVA pathway" ; "acetate-mevalonate pathway" ; "isopentenyl diphosphate anabolism, mevalonate pathway" (for all, see Synonyms field below)
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       3
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 Genes
 isopentenyl diphosphate biosynthetic process, mevalonate pathway (all annotations which use CV term, excluding "NOT" statements)       3
     involved_in | isopentenyl diphosphate biosynthetic process, mevalonate pathway       3
Spanning Tree (Parents/Children)
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acyl-CoA metabolic process
 |__acetyl-CoA metabolic process__________________
phospholipid biosynthetic process                 |
 |__isopentenyl diphosphate biosynthetic process__|
isopentenyl diphosphate metabolic process         |
 |__isopentenyl diphosphate biosynthetic process__|
                                                  isopentenyl diphosphate biosynthetic process, mevalonate pathway  3 rec.
                                                   |__isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process
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Is a acetyl-CoA metabolic process
isopentenyl diphosphate biosynthetic process
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Synonyms
  • "Ac-MVA pathway" EXACT[ PubMed:14517367 ]
    "acetate-mevalonate pathway" EXACT[ PubMed:14517367 ]
    "isopentenyl diphosphate anabolism, mevalonate pathway" EXACT
    "isopentenyl diphosphate biosynthetic process via mevalonate" EXACT
    "isopentenyl diphosphate formation, mevalonate pathway" EXACT
    "isopentenyl diphosphate synthesis, mevalonate pathway" EXACT
Secondary IDs
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MetaCyc:PWY-922