FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway ID (Ontology) GO:0019288 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.[ PubMed:18948055 ]
Also Known As "isopentenyl diphosphate anabolism, mevalonate-independent pathway" ; "isopentenyl diphosphate biosynthesis, mevalonate-independent" ; "isopentenyl diphosphate biosynthesis, non-mevalonate pathway" (for all, see Synonyms field below)
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Spanning Tree (Parents/Children)
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aldehyde metabolic process
 |__glyceraldehyde-3-phosphate metabolic process__
phosphate-containing compound metabolic process   |
 |__glyceraldehyde-3-phosphate metabolic process__|
phospholipid biosynthetic process                 |
 |__isopentenyl diphosphate biosynthetic process__|
organophosphate metabolic process                 |
 |__glyceraldehyde-3-phosphate metabolic process__|
isopentenyl diphosphate metabolic process         |
 |__isopentenyl diphosphate biosynthetic process__|
carbohydrate derivative metabolic process         |
 |__glyceraldehyde-3-phosphate metabolic process__|
                                                  isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
                                                   |__isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
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Is a isopentenyl diphosphate biosynthetic process
glyceraldehyde-3-phosphate metabolic process
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Synonyms
  • "isopentenyl diphosphate anabolism, mevalonate-independent pathway" EXACT
    "isopentenyl diphosphate biosynthesis, mevalonate-independent" EXACT
    "isopentenyl diphosphate biosynthesis, non-mevalonate pathway" EXACT
    "isopentenyl diphosphate biosynthetic process via 1-deoxy-D-xylulose 5-phosphate" EXACT
    "isopentenyl diphosphate biosynthetic process, MEP pathway" EXACT
    "isopentenyl diphosphate biosynthetic process, mevalonate-independent" EXACT
    "isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway" EXACT
    "isopentenyl diphosphate biosynthetic process, non-mevalonate pathway" EXACT
    "isopentenyl diphosphate formation, mevalonate-independent pathway" EXACT
    "isopentenyl diphosphate synthesis, mevalonate-independent pathway" EXACT
    "mevalonate-independent isopentenyl diphosphate biosynthesis" EXACT
    "mevalonate-independent isopentenyl diphosphate biosynthetic process" EXACT
    "non-MVA pathway" EXACT
Secondary IDs
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MetaCyc:NONMEVIPP-PWY