FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term modification-dependent protein catabolic process ID (Ontology) GO:0019941 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.
Also Known As "modification-dependent protein breakdown" ; "modification-dependent protein catabolism" ; "modification-dependent protein degradation" (for all, see Synonyms field below)
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       7
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 modification-dependent protein catabolic process (all annotations which use CV term, excluding "NOT" statements)       7
     involved_in | modification-dependent protein catabolic process       7
Spanning Tree (Parents/Children)
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proteolysis
 |__proteolysis involved in protein catabolic process_______
macromolecule catabolic process                             |
 |__modification-dependent macromolecule catabolic process__|
protein catabolic process                                   |
 |__proteolysis involved in protein catabolic process_______|
                                                            modification-dependent protein catabolic process  362 rec.
                                                             |__oxidation-dependent protein catabolic process
                                                             |__prenylated protein catabolic process
                                                             |__ubiquitin-dependent protein catabolic process 355 rec.
                                                                 |__proteasome-mediated ubiquitin-dependent protein catabolic process(+) 270 rec.
                                                                 |__protein arginylation
                                                                 |__protein deubiquitination involved in ubiquitin-dependent protein catabolic process 1 rec.
                                                                 |__regulation of ubiquitin-dependent protein catabolic process(+) 71 rec.
                                                                 |__ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(+) 14 rec.
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Is a modification-dependent macromolecule catabolic process
proteolysis involved in protein catabolic process
Part of
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Synonyms
  • "modification-dependent protein breakdown" EXACT
    "modification-dependent protein catabolism" EXACT
    "modification-dependent protein degradation" EXACT
    "modification-dependent proteolysis" EXACT
    "modification-initiated protein catabolic process" EXACT
    "modification-initiated protein catabolism" EXACT
    "modification-initiated proteolysis" EXACT
    "protein degradation tagging activity" RELATED
    "protein-ligand-dependent protein catabolic process" NARROW
    "protein-ligand-dependent protein catabolism" NARROW
Secondary IDs
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