FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term midbrain-hindbrain boundary initiation ID (Ontology) GO:0021547 (Gene Ontology)
Definition The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.[ PubMed:15541513 ]
Also Known As "MHB biosynthesis" ; "MHB formation" ; "midbrain-hindbrain boundary biosynthesis" (for all, see Synonyms field below)
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pattern specification process
 |__regionalization_______________________________________
brain development                                         |
 |__midbrain-hindbrain boundary development_______________|
anterior/posterior pattern specification                  |
 |__neural plate anterior/posterior regionalization_______|
rostrocaudal neural tube patterning                       |
 |__midbrain-hindbrain boundary development_______________|
anatomical structure formation involved in morphogenesis  |
 |__formation of anatomical boundary______________________|
anatomical structure development                          |
 |__midbrain-hindbrain boundary development_______________|
neural plate regionalization                              |
 |__neural plate anterior/posterior regionalization_______|
                                                          midbrain-hindbrain boundary initiation
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Is a regionalization
formation of anatomical boundary
Part of neural plate anterior/posterior regionalization
midbrain-hindbrain boundary development
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Synonyms
  • "isthmus biosynthesis" RELATED
    "isthmus formation" RELATED
    "MHB biosynthesis" EXACT
    "MHB formation" EXACT
    "midbrain-hindbrain boundary biosynthesis" EXACT
    "midbrain-hindbrain boundary formation" EXACT
Secondary IDs
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