FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term CCR4-NOT complex ID (Ontology) GO:0030014 (Gene Ontology)
Definition The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8.[ PubMed:11113136 PubMed:11239395 PubMed:22785621 PubMed:30601114 ]
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT      11
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 Gene Groups Genes
 CCR4-NOT complex (all annotations which use CV term, excluding "NOT" statements)       1     11
     part_of | CCR4-NOT complex       --      11
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  protein-containing complex
   |__intracellular protein-containing complex
       |__CCR4-NOT complex  14 rec.
           |__CCR4-NOT core complex 9 rec.
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Is a intracellular protein-containing complex
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