FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term muscle filament sliding ID (Ontology) GO:0030049 (Gene Ontology)
Definition The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.[ ISBN:0815316194 ]
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muscle system process
 |__muscle contraction_____________
actin-mediated cell contraction    |
 |__actin-myosin filament sliding__|
                                   muscle filament sliding
                                    |__regulation of muscle filament sliding
                                        |__negative regulation of muscle filament sliding
                                        |__positive regulation of muscle filament sliding
                                        |__regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction(+)
                                        |__regulation of muscle filament sliding speed(+)
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Is a actin-myosin filament sliding
Part of muscle contraction
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Reactome:R-HSA-390522 "Striated Muscle Contraction"