FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term hemidesmosome ID (Ontology) GO:0030056 (Gene Ontology)
Definition A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces.[ ISBN:0815316208 PubMed:20205195 ]
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  anchoring junction
   |__cell-substrate junction
       |__hemidesmosome
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Is a cell-substrate junction
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Synonyms
  • "epidermal attachment structure" NARROW
    "fibrous organelle" NARROW[ PubMed:20205195 ]
    "hemi-adherens junction" RELATED
    "trans-epithelial attachment" NARROW[ PubMed:20205195 ]
Secondary IDs
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Wikipedia:Hemidesmosome