FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term insulin processing ID (Ontology) GO:0030070 (Gene Ontology)
Definition The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.[ ISBN:0198506732 ]
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protein metabolic process
 |__insulin metabolic process___________________
hormone metabolic process                       |
 |__peptide hormone processing__________________|
amide metabolic process                         |
 |__peptide hormone processing__________________|
signaling receptor ligand precursor processing  |
 |__peptide hormone processing__________________|
                                                insulin processing
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Is a peptide hormone processing
insulin metabolic process
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Reactome:R-HSA-264876 "Insulin processing"