FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term lymphocyte differentiation ID (Ontology) GO:0030098 (Gene Ontology)
Definition The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
Also Known As "lymphocyte cell differentiation" ; "lymphocytic blood cell differentiation"
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leukocyte differentiation
 |__mononuclear cell differentiation__
leukocyte activation                  |
 |__lymphocyte activation_____________|
                                      lymphocyte differentiation
                                       |__B cell differentiation
                                       |   |__B cell lineage commitment(+)
                                       |   |__B cell selection(+)
                                       |   |__immature B cell differentiation(+)
                                       |   |__mature B cell differentiation(+)
                                       |   |__regulation of B cell differentiation(+)
                                       |__natural killer cell differentiation
                                       |   |__natural killer cell differentiation involved in immune response(+)
                                       |   |__regulation of natural killer cell differentiation(+)
                                       |__regulation of lymphocyte differentiation
                                       |   |__negative regulation of lymphocyte differentiation(+)
                                       |   |__positive regulation of lymphocyte differentiation(+)
                                       |   |__regulation of B cell differentiation(+)
                                       |   |__regulation of natural killer cell differentiation(+)
                                       |   |__regulation of T cell differentiation(+)
                                       |__T cell differentiation
                                           |__alpha-beta T cell differentiation(+)
                                           |__cytotoxic T cell differentiation(+)
                                           |__exhausted T cell differentiation
                                           |__extrathymic T cell differentiation(+)
                                           |__gamma-delta T cell differentiation(+)
                                           |__pro-T cell differentiation(+)
                                           |__regulation of T cell differentiation(+)
                                           |__regulatory T cell differentiation(+)
                                           |__somatic diversification of T cell receptor genes(+)
                                           |__T cell differentiation in thymus(+)
                                           |__T cell differentiation involved in immune response(+)
                                           |__T cell lineage commitment(+)
                                           |__T cell selection(+)
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Is a lymphocyte activation
mononuclear cell differentiation
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Synonyms
  • "lymphocyte cell differentiation" EXACT
    "lymphocyte development" RELATED
    "lymphocytic blood cell differentiation" EXACT
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