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General Information
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| Term |
AP-2 adaptor complex |
ID (Ontology) |
GO:0030122 (Gene Ontology) |
| Definition |
A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).[ PubMed:10611976 PubMed:21097499 PubMed:22022230 PubMed:24322426 ] |
| Also Known As |
"HA2" ; "HA2 clathrin adaptor" |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_CELLULAR_COMPONENT | 6 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Gene Groups | Genes |
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AP-2 adaptor complex (all annotations which use CV term, excluding "NOT" statements) | 1 | 6 | part_of | AP-2 adaptor complex | -- | 6 |
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Relationships
