FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term negative regulation of Wnt signaling pathway ID (Ontology) GO:0030178 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
Also Known As "down regulation of frizzled signaling pathway" ; "down regulation of Wnt receptor signaling pathway" ; "down-regulation of frizzled signaling pathway" (for all, see Synonyms field below)
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       5
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 negative regulation of Wnt signaling pathway (all annotations which use CV term, excluding "NOT" statements)       5
     involved_in | negative regulation of Wnt signaling pathway       5
Spanning Tree (Parents/Children)
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regulation of signal transduction
 |__negative regulation of signal transduction__
 |__regulation of Wnt signaling pathway_________|
negative regulation of cell communication       |
 |__negative regulation of signal transduction__|
Wnt signaling pathway                           |
 |__regulation of Wnt signaling pathway_________|
negative regulation of signaling                |
 |__negative regulation of signal transduction__|
negative regulation of response to stimulus     |
 |__negative regulation of signal transduction__|
                                                negative regulation of Wnt signaling pathway  53 rec.
                                                 |__negative regulation of canonical Wnt signaling pathway 51 rec.
                                                 |__negative regulation of non-canonical Wnt signaling pathway
                                                 |   |__negative regulation of Frizzled Nuclear Import pathway
                                                 |   |__negative regulation of Wnt signaling pathway, calcium modulating pathway
                                                 |   |__negative regulation of Wnt signaling pathway, planar cell polarity pathway
                                                 |__negative regulation of Wnt signaling pathway involved in heart development
                                                 |__Wnt receptor catabolic process
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Is a negative regulation of signal transduction
regulation of Wnt signaling pathway
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Synonyms
  • "down regulation of frizzled signaling pathway" EXACT
    "down regulation of Wnt receptor signaling pathway" EXACT
    "down-regulation of frizzled signaling pathway" EXACT
    "down-regulation of Wnt receptor signaling pathway" EXACT
    "downregulation of frizzled signaling pathway" EXACT
    "downregulation of Wnt receptor signaling pathway" EXACT
    "inhibition of frizzled signaling pathway" NARROW
    "inhibition of Wnt receptor signaling pathway" NARROW
    "negative regulation of frizzled signaling pathway" EXACT
    "negative regulation of frizzled signalling pathway" EXACT
    "negative regulation of Wnt receptor signaling pathway" EXACT
    "negative regulation of Wnt receptor signalling pathway" EXACT
    "negative regulation of Wnt-activated signaling pathway" EXACT
Secondary IDs
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