FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term negative regulation of transforming growth factor beta receptor signaling pathway ID (Ontology) GO:0030512 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
Also Known As "down regulation of transforming growth factor beta receptor signaling pathway" ; "down-regulation of transforming growth factor beta receptor signaling pathway" ; "downregulation of transforming growth factor beta receptor signaling pathway" (for all, see Synonyms field below)
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negative regulation of signal transduction
 |__negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway__
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway               |
 |__regulation of transforming growth factor beta receptor signaling pathway_________________________|
 |__negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway__|
regulation of cellular response to transforming growth factor beta stimulus                          |
 |__regulation of transforming growth factor beta receptor signaling pathway_________________________|
                                                                                         negative regulation of transforming growth factor beta receptor signaling pathway
                                                                                          |__sequestering of TGFbeta in extracellular matrix
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Is a regulation of transforming growth factor beta receptor signaling pathway
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
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Synonyms
  • "down regulation of transforming growth factor beta receptor signaling pathway" EXACT
    "down-regulation of transforming growth factor beta receptor signaling pathway" EXACT
    "downregulation of transforming growth factor beta receptor signaling pathway" EXACT
    "inhibition of transforming growth factor beta receptor signaling pathway" NARROW
    "negative regulation of TGF-beta receptor signaling pathway" EXACT
    "negative regulation of TGFbeta receptor signaling pathway" EXACT
    "negative regulation of transforming growth factor beta receptor signalling pathway" EXACT
Secondary IDs
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Reactome:R-HSA-2173788 "Downregulation of TGF-beta receptor signaling"