FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term retromer, tubulation complex ID (Ontology) GO:0030905 (Gene Ontology)
Definition The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodeling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6.[ PubMed:26220253 PubMed:9700157 ]
Also Known As "heterodimeric membrane-deforming retromer subcomplex" ; "retromer complex, outer shell" ; "SNX-BAR dimer"
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       2
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 Genes
 retromer, tubulation complex (all annotations which use CV term, excluding "NOT" statements)       2
     part_of | retromer, tubulation complex       2
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  protein-containing complex
   |__membrane protein complex
       |__retromer, tubulation complex  2 rec.
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Is a membrane protein complex
Part of retromer complex
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Synonyms
  • "heterodimeric membrane-deforming retromer subcomplex" EXACT[ PubMed:22193161 ]
    "retromer complex, outer shell" EXACT
    "SNX-BAR dimer" EXACT[ PubMed:26220253 ]
Secondary IDs
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