FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term retrograde protein transport, ER to cytosol ID (Ontology) GO:0030970 (Gene Ontology)
Definition The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon.[ PubMed:11994744 ]
Also Known As "protein dislocation from ER" ; "protein retrotranslocation, ER to cytosol" ; "retrograde protein transport, endoplasmic reticulum to cytosol"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       3
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 Genes
 retrograde protein transport, ER to cytosol (all annotations which use CV term, excluding "NOT" statements)       3
     involved_in | retrograde protein transport, ER to cytosol       3
Spanning Tree (Parents/Children)
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intracellular protein transport
 |__protein exit from endoplasmic reticulum_____
proteasomal protein catabolic process           |
 |__ERAD pathway________________________________|
response to endoplasmic reticulum stress        |
 |__ERAD pathway________________________________|
response to chemical                            |
 |__ERAD pathway________________________________|
intracellular transport                         |
 |__endoplasmic reticulum to cytosol transport__|
                                                retrograde protein transport, ER to cytosol  4 rec.
                                                 |__membrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                 |__regulation of retrograde protein transport, ER to cytosol 1 rec.
                                                     |__negative regulation of retrograde protein transport, ER to cytosol 1 rec.
                                                     |__positive regulation of retrograde protein transport, ER to cytosol
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Is a protein exit from endoplasmic reticulum
endoplasmic reticulum to cytosol transport
Part of ERAD pathway
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Synonyms
  • "protein dislocation from ER" EXACT
    "protein retrotranslocation, ER to cytosol" EXACT
    "retrograde protein transport, endoplasmic reticulum to cytosol" EXACT
Secondary IDs
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