FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term programmed DNA elimination by chromosome breakage ID (Ontology) GO:0031052 (Gene Ontology)
Definition Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage.[ PubMed:15956677 PubMed:25303953 PubMed:32165395 ]
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  negative regulation of gene expression
   |__programmed DNA elimination
       |__programmed DNA elimination by chromosome breakage
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  • "chromosome breakage" RELATED
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