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| Term | death-inducing signaling complex | ID (Ontology) | GO:0031264 (Gene Ontology) |
| Definition | A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10.[ PubMed:12628743 PubMed:12655293 PubMed:8521815 ] | ||
| Also Known As | "death receptor-induced signaling complex" ; "death receptor-induced signalling complex" ; "death-inducing signalling complex" (for all, see Synonyms field below) | ||
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plasma membrane___________ membrane protein complex__| plasma membrane protein complex |__death-inducing signaling complex 1 rec. |__CD95 death-inducing signaling complex 1 rec. |__TRAIL death-inducing signaling complex |
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| Is a | plasma membrane protein complex | ||
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| Wikipedia:Death-inducing_signaling_complex | |||
