FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term DNA integrity checkpoint signaling ID (Ontology) GO:0031570 (Gene Ontology)
Definition A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.
Also Known As "DNA integrity checkpoint" ; "signal transduction involved in DNA integrity checkpoint"
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intracellular signal transduction___________________
negative regulation of cell cycle phase transition__|
                                                    cell cycle checkpoint signaling
                                                     |__DNA integrity checkpoint signaling  44 rec.
                                                         |__DNA damage checkpoint signaling 38 rec.
                                                         |   |__mitotic DNA damage checkpoint signaling(+) 24 rec.
                                                         |   |__regulation of DNA damage checkpoint(+) 2 rec.
                                                         |__DNA replication checkpoint signaling 18 rec.
                                                         |   |__meiotic G2/MI DNA replication checkpoint signaling
                                                         |   |__mitotic DNA replication checkpoint signaling 12 rec.
                                                         |__meiotic DNA integrity checkpoint signaling 1 rec.
                                                         |   |__meiotic G2/MI DNA replication checkpoint signaling
                                                         |__mitotic DNA integrity checkpoint signaling 29 rec.
                                                             |__mitotic DNA damage checkpoint signaling(+) 24 rec.
                                                             |__mitotic DNA replication checkpoint signaling 12 rec.
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Is a cell cycle checkpoint signaling
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Synonyms
  • "DNA integrity checkpoint" EXACT
    "signal transduction involved in DNA integrity checkpoint" EXACT
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