General Information
Term	cytoplasm to vacuole targeting by the Cvt pathway	ID (Ontology)	GO:0032258 (Gene Ontology)
Definition	A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast.[ PubMed:12865942 PubMed:15659643 ]
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General Information

Term

cytoplasm to vacuole targeting by the Cvt pathway

ID (Ontology)

GO:0032258 (Gene Ontology)

Definition

A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast.[ PubMed:12865942 PubMed:15659643 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

protein targeting
 |__protein targeting to vacuole__________________
intracellular protein transport                   |
 |__protein targeting to vacuole__________________|
vacuolar transport                                |
 |__protein targeting to vacuole__________________|
cellular process                                  |
 |__process utilizing autophagic mechanism________|
protein localization to vacuole                   |
 |__protein targeting to vacuole__________________|
establishment of protein localization to vacuole  |
 |__protein targeting to vacuole__________________|
                                                  cytoplasm to vacuole targeting by the Cvt pathway

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Is a	protein targeting to vacuole process utilizing autophagic mechanism
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protein targeting to vacuole
process utilizing autophagic mechanism

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