FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term AMPA glutamate receptor complex ID (Ontology) GO:0032281 (Gene Ontology)
Definition An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.
Also Known As "alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex" ; "AMPA-selective glutamate receptor complex"
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monoatomic ion channel complex_____
neurotransmitter receptor complex__|
                                   ionotropic glutamate receptor complex
                                    |__AMPA glutamate receptor complex
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Is a ionotropic glutamate receptor complex
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Synonyms
  • "alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex" EXACT
    "AMPA receptor" RELATED
    "AMPA-selective glutamate receptor complex" EXACT
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