FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term MutLalpha complex ID (Ontology) GO:0032389 (Gene Ontology)
Definition A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
Also Known As "MLH1/PMS2 complex" ; "MutL-alpha complex"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       2
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 MutLalpha complex (all annotations which use CV term, excluding "NOT" statements)       1      2
     part_of | MutLalpha complex       --       2
Spanning Tree (Parents/Children)
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intracellular anatomical structure
 |__mismatch repair complex_____________
nucleus                                 |
 |__nuclear protein-containing complex__|
protein-containing complex              |
 |__mismatch repair complex_____________|
 |__nuclear protein-containing complex__|
                                        MutLalpha complex  3 rec.
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Is a mismatch repair complex
nuclear protein-containing complex
Part of
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Synonyms
  • "MLH1/PMS2 complex" EXACT
    "MMR complex" BROAD
    "MutL-alpha complex" EXACT
Secondary IDs
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