FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term chemokine production ID (Ontology) GO:0032602 (Gene Ontology)
Definition The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.[ ISBN:0198506732 PubMed:12183377 ]
Also Known As "chemokine anabolism" ; "chemokine biosynthesis" ; "chemokine formation" (for all, see Synonyms field below)
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Spanning Tree (Parents/Children)
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gene expression___________________
multicellular organismal process__|
                                  cytokine production
                                   |__chemokine production
                                       |__chemokine (C-C motif) ligand 1 production
                                       |   |__regulation of chemokine (C-C motif) ligand 1 production(+)
                                       |__chemokine (C-C motif) ligand 4 production
                                       |   |__regulation of chemokine (C-C motif) ligand 4 production(+)
                                       |__chemokine (C-C motif) ligand 5 production
                                       |   |__regulation of chemokine (C-C motif) ligand 5 production(+)
                                       |__chemokine (C-C motif) ligand 6 production
                                       |   |__regulation of chemokine (C-C motif) ligand 6 production(+)
                                       |__chemokine (C-C motif) ligand 11 production
                                       |__chemokine (C-C motif) ligand 17 production
                                       |__chemokine (C-C motif) ligand 19 production
                                       |__chemokine (C-C motif) ligand 20 production
                                       |   |__regulation of chemokine (C-C motif) ligand 20 production(+)
                                       |__chemokine (C-C motif) ligand 21 production
                                       |__chemokine (C-C motif) ligand 22 production
                                       |__chemokine (C-X-C motif) ligand 1 production
                                       |   |__regulation of chemokine (C-X-C motif) ligand 1 production(+)
                                       |__chemokine (C-X-C motif) ligand 2 production
                                       |   |__regulation of chemokine (C-X-C motif) ligand 2 production(+)
                                       |__chemokine (C-X-C motif) ligand 9 production
                                       |   |__regulation of chemokine (C-X-C motif) ligand 9 production(+)
                                       |__chemokine (C-X-C motif) ligand 12 production
                                       |__chemokine (C-X-C motif) ligand 13 production
                                       |__chemokine (C-X-C motif) ligand 16 production
                                       |__fractalkine production
                                       |   |__regulation of fractalkine production(+)
                                       |__IP-10 production
                                       |   |__regulation of IP-10 production(+)
                                       |__macrophage inflammatory protein-1 alpha production
                                       |   |__regulation of macrophage inflammatory protein 1 alpha production(+)
                                       |__macrophage inflammatory protein-1 gamma production
                                       |   |__regulation of macrophage inflammatory protein-1 gamma production(+)
                                       |__monocyte chemotactic protein-1 production
                                       |   |__regulation of monocyte chemotactic protein-1 production(+)
                                       |__regulation of chemokine production
                                       |   |__negative regulation of chemokine production(+)
                                       |   |__positive regulation of chemokine production(+)
                                       |   |__regulation of chemokine (C-C motif) ligand 1 production(+)
                                       |   |__regulation of chemokine (C-C motif) ligand 4 production(+)
                                       |   |__regulation of chemokine (C-C motif) ligand 5 production(+)
                                       |   |__regulation of chemokine (C-C motif) ligand 6 production(+)
                                       |   |__regulation of chemokine (C-C motif) ligand 20 production(+)
                                       |   |__regulation of chemokine (C-X-C motif) ligand 1 production(+)
                                       |   |__regulation of chemokine (C-X-C motif) ligand 2 production(+)
                                       |   |__regulation of chemokine (C-X-C motif) ligand 9 production(+)
                                       |   |__regulation of fractalkine production(+)
                                       |   |__regulation of IP-10 production(+)
                                       |   |__regulation of macrophage inflammatory protein 1 alpha production(+)
                                       |   |__regulation of macrophage inflammatory protein-1 gamma production(+)
                                       |   |__regulation of monocyte chemotactic protein-1 production(+)
                                       |__thymic stromal lymphopoietin production
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Synonyms
  • "chemokine anabolism" EXACT
    "chemokine biosynthesis" EXACT
    "chemokine biosynthetic process" NARROW
    "chemokine formation" EXACT
    "chemokine metabolic process" NARROW
    "chemokine secretion" NARROW
    "chemokine synthesis" EXACT
Secondary IDs
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