FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term super elongation complex ID (Ontology) GO:0032783 (Gene Ontology)
Definition A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae.[ PubMed:17150956 PubMed:30102332 ]
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       8
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 Gene Groups Genes
 super elongation complex (all annotations which use CV term, excluding "NOT" statements)       1      8
     part_of | super elongation complex       --       8
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nucleoplasm_________________________
nuclear protein-containing complex__|
                                    transcription elongation factor complex
                                     |__super elongation complex  9 rec.
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Is a transcription elongation factor complex
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Synonyms
  • "ELL-EAF complex" NARROW
    "ELL-EAF-EBP complex" NARROW
Secondary IDs
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