FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term macrolide biosynthetic process ID (Ontology) GO:0033068 (Gene Ontology)
Definition The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.[ ISBN:0198506732 PubMed:17298179 ]
Also Known As "macrolide anabolism" ; "macrolide biosynthesis" ; "macrolide formation" (for all, see Synonyms field below)
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Spanning Tree (Parents/Children)
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biosynthetic process
 |__antibiotic biosynthetic process________
 |__lactone biosynthetic process___________|
antibiotic metabolic process               |
 |__antibiotic biosynthetic process________|
 |__macrolide metabolic process____________|
polyketide metabolic process               |
 |__polyketide biosynthetic process________|
 |__macrolide metabolic process____________|
secondary metabolite biosynthetic process  |
 |__polyketide biosynthetic process________|
lactone metabolic process                  |
 |__macrolide metabolic process____________|
 |__lactone biosynthetic process___________|
                                           macrolide biosynthetic process
                                            |__enterobactin biosynthetic process
                                            |__epothilone biosynthetic process
                                            |__erythromycin biosynthetic process
                                            |__zearalenone biosynthetic process
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Is a antibiotic biosynthetic process
polyketide biosynthetic process
macrolide metabolic process
lactone biosynthetic process
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Synonyms
  • "macrolide anabolism" EXACT
    "macrolide biosynthesis" EXACT
    "macrolide formation" EXACT
    "macrolide synthesis" EXACT
Secondary IDs
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