FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term CORVET complex ID (Ontology) GO:0033263 (Gene Ontology)
Definition A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.[ PubMed:17488625 ]
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Annotations
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       6
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Relevant FlyBase reports
 Gene Groups Genes
 CORVET complex (all annotations which use CV term, excluding "NOT" statements)       1      6
     part_of | CORVET complex       --       6
Spanning Tree (Parents/Children)
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endomembrane system
 |__endosome___________________
cytoplasmic vesicle            |
 |__endosome___________________|
protein-containing complex     |
 |__vesicle tethering complex__|
                               CORVET complex  7 rec.
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Is a vesicle tethering complex
Part of endosome
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