FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term Rpd3L complex ID (Ontology) GO:0033698 (Gene Ontology)
Definition A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a two copies of catalytic histone deacetylase subunit (S. pombe Clr6/ S. cerevisiae Rpd3p), an Sds-3 family protein (S. pombe /S. cerevisiae Sds3(p) ), two copies of SIN3 family co-repressor (S. pombe Pst1/ S. cerevisiae Sin3p, a WD repeat protein/ histone chaperone (S. pombe Prw1/ S. cerevisiae Ume1p), and a zf- PHD finger ( S. pombe Png2/ S. cerevisiae Pho23p), plus 4 additional subunits, and associated factors.[ PubMed:17450151 ]
Also Known As "Clr6 histone deacetylase complex I/I'" ; "Clr6L complex" ; "Rpd3C(L)" (for all, see Synonyms field below)
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histone deacetylase complex__
nuclear chromosome___________|
chromatin____________________|
                             Sin3-type complex
                              |__Rpd3L complex
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