FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term CFTR-NHERF-ezrin complex ID (Ontology) GO:0034662 (Gene Ontology)
Definition A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity.[ PubMed:16129695 PubMed:16798722 PubMed:16926444 ]
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plasma membrane___________
membrane protein complex__|
                          plasma membrane protein complex
                           |__CFTR-NHERF-ezrin complex
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