FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term protein folding in endoplasmic reticulum ID (Ontology) GO:0034975 (Gene Ontology)
Definition A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).
Also Known As "oxidative protein folding" ; "protein folding in ER"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       4
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 Genes
 protein folding in endoplasmic reticulum (all annotations which use CV term, excluding "NOT" statements)       4
     involved_in | protein folding in endoplasmic reticulum       4
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cellular process____
protein maturation__|
                    protein folding
                     |__protein folding in endoplasmic reticulum  4 rec.
                         |__regulation of protein folding in endoplasmic reticulum
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Synonyms
  • "oxidative protein folding" EXACT[ PubMed:25091901 ]
    "protein folding in ER" EXACT
Secondary IDs
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