FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term endocrine system development ID (Ontology) GO:0035270 (Gene Ontology)
Definition Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.
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multicellular organism development__
anatomical structure development____|
                                    system development
                                     |__endocrine system development  5 rec.
                                         |__adrenal gland development
                                         |   |__adrenal chromaffin cell differentiation
                                         |   |__adrenal cortex development(+)
                                         |__endocrine pancreas development
                                         |   |__pancreatic A cell differentiation(+)
                                         |   |__pancreatic D cell differentiation(+)
                                         |   |__pancreatic epsilon cell differentiation(+)
                                         |   |__pancreatic PP cell differentiation(+)
                                         |   |__type B pancreatic cell differentiation(+)
                                         |__parathyroid gland development
                                         |   |__neural crest cell differentiation involved in parathyroid gland development
                                         |__pineal gland development
                                         |__pituitary gland development
                                         |   |__adenohypophysis development(+)
                                         |   |__hypophysis morphogenesis(+)
                                         |   |__neurohypophysis development(+)
                                         |__ring gland development 5 rec.
                                         |__thyroid gland development
                                             |__thyroid gland epithelial cell proliferation(+)
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