FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term miRNA-mediated gene silencing by inhibition of translation ID (Ontology) GO:0035278 (Gene Ontology)
Definition An RNA interference pathway in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.[ PubMed:14744438 PubMed:15196554 ]
Also Known As "down regulation of translation involved in gene silencing by miRNA" ; "down-regulation of translation involved in gene silencing by miRNA" ; "downregulation of translation involved in gene silencing by miRNA" (for all, see Synonyms field below)
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      15
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 Genes
 miRNA-mediated gene silencing by inhibition of translation (all annotations which use CV term, excluding "NOT" statements)      15
     involved_in | miRNA-mediated gene silencing by inhibition of translation      15
Spanning Tree (Parents/Children)
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regulation of translation
 |__negative regulation of translation_________________________
negative regulation of gene expression                         |
 |__negative regulation of translation_________________________|
regulatory ncRNA-mediated post-transcriptional gene silencing  |
 |__miRNA-mediated post-transcriptional gene silencing_________|
negative regulation of protein metabolic process               |
 |__negative regulation of translation_________________________|
                                                               miRNA-mediated gene silencing by inhibition of translation  15 rec.
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Is a negative regulation of translation
miRNA-mediated post-transcriptional gene silencing
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Synonyms
  • "down regulation of translation involved in gene silencing by miRNA" EXACT
    "down-regulation of translation involved in gene silencing by miRNA" EXACT
    "downregulation of translation involved in gene silencing by miRNA" EXACT
    "gene silencing by miRNA, negative regulation of translation" EXACT
    "inhibition of translation involved in gene silencing by miRNA" NARROW
    "miRNA mediated inhibition of translation" EXACT
    "miRNA-mediated gene silencing, negative regulation of translation" RELATED
    "negative regulation of translation involved in gene silencing by microRNA" EXACT
Secondary IDs
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