FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term mitochondrial prohibitin complex ID (Ontology) GO:0035632 (Gene Ontology)
Definition A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death.[ PubMed:12237468 PubMed:21164222 ]
Also Known As "mitochondrial inner membrane prohibitin complex"
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       2
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 mitochondrial prohibitin complex (all annotations which use CV term, excluding "NOT" statements)       2
     part_of | mitochondrial prohibitin complex       2
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mitochondrial inner membrane______________
membrane protein complex__________________|
mitochondrial protein-containing complex__|
                                          inner mitochondrial membrane protein complex
                                           |__mitochondrial prohibitin complex  2 rec.
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Is a inner mitochondrial membrane protein complex
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  • "mitochondrial inner membrane prohibitin complex" EXACT
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