FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term CD4-positive, alpha-beta T cell activation ID (Ontology) GO:0035710 (Gene Ontology)
Definition The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
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  T cell activation
   |__alpha-beta T cell activation
       |__CD4-positive, alpha-beta T cell activation
           |__CD4-positive, alpha-beta T cell differentiation
           |   |__CD4-positive, alpha-beta intraepithelial T cell differentiation
           |   |__CD4-positive, alpha-beta T cell differentiation involved in immune response(+)
           |   |__CD4-positive, alpha-beta T cell lineage commitment(+)
           |   |__CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(+)
           |   |__regulation of CD4-positive, alpha-beta T cell differentiation(+)
           |__CD4-positive, alpha-beta T cell proliferation
           |   |__activated CD4-positive, alpha-beta T cell proliferation
           |   |__regulation of CD4-positive, alpha-beta T cell proliferation(+)
           |__regulation of CD4-positive, alpha-beta T cell activation
           |   |__negative regulation of CD4-positive, alpha-beta T cell activation(+)
           |   |__positive regulation of CD4-positive, alpha-beta T cell activation(+)
           |   |__regulation of CD4-positive, alpha-beta T cell costimulation(+)
           |   |__regulation of CD4-positive, alpha-beta T cell differentiation(+)
           |   |__regulation of CD4-positive, alpha-beta T cell proliferation(+)
           |   |__regulation of T-helper 1 cell activation(+)
           |   |__regulation of T-helper 2 cell activation(+)
           |__T-helper 1 cell activation
           |   |__regulation of T-helper 1 cell activation(+)
           |__T-helper 2 cell activation
               |__regulation of T-helper 2 cell activation(+)
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