FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term 7-methylguanosine cap hypermethylation ID (Ontology) GO:0036261 (Gene Ontology)
Definition Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.[ PubMed:11983179 PubMed:18775984 ]
Also Known As "2,2,7-trimethylguanosine cap formation" ; "conversion of m(7)G to m(3)G" ; "m(7)G cap hypermethylation" (for all, see Synonyms field below)
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 7-methylguanosine cap hypermethylation (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | 7-methylguanosine cap hypermethylation       1
Spanning Tree (Parents/Children)
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RNA 5'-end processing
 |__RNA capping____________
RNA modification           |
 |__RNA methylation________|
macromolecule methylation  |
 |__RNA methylation________|
                           7-methylguanosine cap hypermethylation  1 rec.
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Synonyms
  • "2,2,7-trimethylguanosine cap formation" EXACT[ PubMed:11983179 ]
    "conversion of m(7)G to m(3)G" EXACT[ PubMed:11983179 ]
    "hypermethylation of snoRNA cap" NARROW
    "hypermethylation of snRNA cap" NARROW
    "m(7)G cap hypermethylation" EXACT
    "snoRNA capping" NARROW
    "snRNA capping" NARROW
    "TMG cap formation" EXACT[ PubMed:11983179 ]
Secondary IDs
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