FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term Fas signaling pathway ID (Ontology) GO:0036337 (Gene Ontology)
Definition The series of molecular signals initiated by the binding of a ligand to a Fas receptor on the surface of the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.[ PubMed:12040174 ]
Also Known As "Apo-1 signaling pathway" ; "CD95 signaling pathway" ; "Fas receptor signaling pathway" (for all, see Synonyms field below)
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  signal transduction
   |__cell surface receptor signaling pathway
       |__Fas signaling pathway
           |__regulation of Fas signaling pathway
               |__negative regulation of Fas signaling pathway
               |__positive regulation of Fas signaling pathway
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Is a cell surface receptor signaling pathway
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Synonyms
  • "Apo-1 signaling pathway" EXACT[ PubMed:12040174 ]
    "CD95 signaling pathway" EXACT[ PubMed:12040174 ]
    "FAS ligand-Fas signaling pathway" NARROW[ PubMed:12040174 ]
    "Fas receptor signaling pathway" EXACT
    "Fas-FasL signaling pathway" NARROW
    "FasL signaling pathway" RELATED
    "FasR signaling pathway" EXACT
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