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| Term | TCR signalosome | ID (Ontology) | GO:0036398 (Gene Ontology) |
| Definition | A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology.[ PubMed:17534068 PubMed:20107804 PubMed:22426112 ] | ||
| Also Known As | "LAT signalosome" ; "linker for activation of T cells signalosome" | ||
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cellular_component |__protein-containing complex |__TCR signalosome |
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| Is a | protein-containing complex | ||
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