FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term synaptic vesicle recycling ID (Ontology) GO:0036465 (Gene Ontology)
Definition The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane.[ PubMed:15217342 PubMed:22026965 PubMed:23245563 ]
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       2
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 Genes
 synaptic vesicle recycling (all annotations which use CV term, excluding "NOT" statements)       2
     involved_in | synaptic vesicle recycling       2
Spanning Tree (Parents/Children)
Only view relationship: 
establishment of localization
 |__transport______________________________
 |__establishment of localization in cell__|
cellular localization                      |
 |__establishment of localization in cell__|
establishment of localization in cell      |
 |__synaptic vesicle cycle_________________|
vesicle-mediated transport in synapse      |
 |__synaptic vesicle cycle_________________|
                                           synaptic vesicle recycling  43 rec.
                                            |__regulation of synaptic vesicle recycling 10 rec.
                                            |   |__negative regulation of synaptic vesicle recycling(+) 1 rec.
                                            |   |__positive regulation of synaptic vesicle recycling(+) 3 rec.
                                            |   |__regulation of recycling endosome localization within postsynapse
                                            |   |__regulation of synaptic vesicle endocytosis(+) 9 rec.
                                            |__synaptic vesicle endocytosis 37 rec.
                                            |   |__bulk synaptic vesicle endocytosis 6 rec.
                                            |   |__clathrin-dependent synaptic vesicle endocytosis 7 rec.
                                            |   |__regulation of synaptic vesicle endocytosis(+) 9 rec.
                                            |   |__synaptic vesicle budding from presynaptic endocytic zone membrane(+) 1 rec.
                                            |   |__synaptic vesicle uncoating(+)
                                            |__synaptic vesicle recycling via endosome 12 rec.
                                                |__clathrin-dependent synaptic vesicle endocytosis 7 rec.
                                                |__endocytosed synaptic vesicle processing via endosome
                                                |__endocytosed synaptic vesicle to endosome fusion
                                                |__regulation of recycling endosome localization within postsynapse
                                                |__synaptic vesicle budding from endosome 1 rec.
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Is a transport
establishment of localization in cell
Part of synaptic vesicle cycle
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