General Information
Term	neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	ID (Ontology)	GO:0036483 (Gene Ontology)
Definition	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.[ PubMed:21113145 ]
Also Known As	"endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway" ; "ER stress-induced neuron intrinsic apoptotic signaling pathway"
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General Information

Term

neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

ID (Ontology)

GO:0036483 (Gene Ontology)

Definition

The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.[ PubMed:21113145 ]

Also Known As

"endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway" ; "ER stress-induced neuron intrinsic apoptotic signaling pathway"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

apoptotic process
 |__neuron apoptotic process___________________________________________________________
response to endoplasmic reticulum stress                                               |
 |__intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress__|
intrinsic apoptotic signaling pathway                                                  |
 |__intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress__|
                                                                                       neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
                                                                                        |__regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway
                                                                                            |__negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway

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Is a	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Part of	neuron apoptotic process
Synonyms & Secondary IDs
Synonyms
	"endoplasmic reticulum stress-induced neuron apoptosis" BROAD "endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway" EXACT "ER stress-induced neuron apoptosis" BROAD "ER stress-induced neuron intrinsic apoptotic signaling pathway" EXACT
Secondary IDs

External Crossreferences & Linkouts

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Relationships

Is a

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Part of

neuron apoptotic process

Synonyms & Secondary IDs

Synonyms

"endoplasmic reticulum stress-induced neuron apoptosis" BROAD
"endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway" EXACT
"ER stress-induced neuron apoptosis" BROAD
"ER stress-induced neuron intrinsic apoptotic signaling pathway" EXACT

Secondary IDs

External Crossreferences & Linkouts