FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ID (Ontology) GO:0036483 (Gene Ontology)
Definition The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.[ PubMed:21113145 ]
Also Known As "endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway" ; "ER stress-induced neuron intrinsic apoptotic signaling pathway"
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response to endoplasmic reticulum stress__
intrinsic apoptotic signaling pathway_____|
                                          intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
                                           |__neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
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Is a intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Part of neuron apoptotic process
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Synonyms
  • "endoplasmic reticulum stress-induced neuron apoptosis" BROAD
    "endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway" EXACT
    "ER stress-induced neuron apoptosis" BROAD
    "ER stress-induced neuron intrinsic apoptotic signaling pathway" EXACT
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