FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term regulation of signal transduction by receptor internalization ID (Ontology) GO:0038009 (Gene Ontology)
Definition Any process that modulates the frequency, rate or extent of signal transduction by the movement of a signaling receptor from the plasma membrane to the inside of the cell. Receptor internalization can have a positive or negative effect on a signaling pathway.[ PubMed:17011816 PubMed:19696798 ]
Also Known As "regulation of signaling pathway by receptor endocytosis"
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receptor-mediated endocytosis
 |__receptor internalization___________
regulation of cell communication       |
 |__regulation of signal transduction__|
regulation of signaling                |
 |__regulation of signal transduction__|
regulation of response to stimulus     |
 |__regulation of signal transduction__|
                                       regulation of signal transduction by receptor internalization  1 rec.
                                        |__negative regulation of signal transduction by receptor internalization
                                        |   |__negative regulation of insulin receptor signaling pathway by insulin receptor internalization
                                        |__positive regulation of signal transduction by receptor internalization 1 rec.
                                            |__positive regulation of insulin receptor signaling pathway by insulin receptor internalization
                                            |__positive regulation of toll-like receptor 9 signaling pathway by B cell receptor internalization
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Is a regulation of signal transduction
receptor internalization
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  • "regulation of signaling pathway by receptor endocytosis" EXACT
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