FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term positive regulation of signal transduction by receptor internalization ID (Ontology) GO:0038010 (Gene Ontology)
Definition Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. Receptor internalization can enhance signaling by concentrating signaling molecules in one location, or by moving a ligand-activated receptor to the location of downstream signaling proteins. Endosomes for example can serve as important intracellular signaling platforms.[ PubMed:17908284 PubMed:19696798 ]
Also Known As "positive regulation of signaling pathway by receptor endocytosis"
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Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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 positive regulation of signal transduction by receptor internalization (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | positive regulation of signal transduction by receptor internalization       1
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regulation of signal transduction
 |__positive regulation of signal transduction_____________________
 |__regulation of signal transduction by receptor internalization__|
positive regulation of cell communication                          |
 |__positive regulation of signal transduction_____________________|
positive regulation of signaling                                   |
 |__positive regulation of signal transduction_____________________|
receptor internalization                                           |
 |__regulation of signal transduction by receptor internalization__|
positive regulation of response to stimulus                        |
 |__positive regulation of signal transduction_____________________|
                                                                   positive regulation of signal transduction by receptor internalization  1 rec.
                                                                    |__positive regulation of insulin receptor signaling pathway by insulin receptor internalization
                                                                    |__positive regulation of toll-like receptor 9 signaling pathway by B cell receptor internalization
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regulation of signal transduction by receptor internalization
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  • "positive regulation of signaling pathway by receptor endocytosis" EXACT
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