FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term positive regulation of insulin receptor signaling pathway by insulin receptor internalization ID (Ontology) GO:0038015 (Gene Ontology)
Definition Any process in which internalization of an insulin receptor activates or increases the frequency, rate or extent of the insulin receptor signaling pathway. Endocytosis of activated receptors can concentrate receptors within endosomes and allow the insulin receptor to phosphorylate substrates that are spatially distinct from those accessible at the plasma membrane.[ PubMed:9609114 ]
Also Known As "positive regulation of insulin receptor signalling pathway by insulin receptor internalization"
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positive regulation of signal transduction
 |__positive regulation of signal transduction by receptor internalization__
 |__positive regulation of insulin receptor signaling pathway_______________|
receptor internalization                                                    |
 |__insulin receptor internalization________________________________________|
regulation of signal transduction by receptor internalization               |
 |__positive regulation of signal transduction by receptor internalization__|
regulation of insulin receptor signaling pathway                            |
 |__positive regulation of insulin receptor signaling pathway_______________|
positive regulation of cellular response to insulin stimulus                |
 |__positive regulation of insulin receptor signaling pathway_______________|
                                                                            positive regulation of insulin receptor signaling pathway by insulin receptor internalization
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Is a positive regulation of signal transduction by receptor internalization
insulin receptor internalization
positive regulation of insulin receptor signaling pathway
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