FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term ERBB2-ERBB4 signaling pathway ID (Ontology) GO:0038135 (Gene Ontology)
Definition The series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.[ PubMed:16460914 ]
Also Known As "ERBB2-ERBB4 signalling pathway" ; "HER2-HER4 signaling pathway"
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ERBB signaling pathway
 |__ERBB2 signaling pathway__
 |__ERBB4 signaling pathway__|
                             ERBB2-ERBB4 signaling pathway
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Is a ERBB2 signaling pathway
ERBB4 signaling pathway
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Synonyms
  • "ERBB2-ERBB4 signalling pathway" EXACT
    "HER2-HER4 signaling pathway" EXACT
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