FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term ERBB4-EGFR signaling pathway ID (Ontology) GO:0038137 (Gene Ontology)
Definition The series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors EGFR (epidermal growth factor receptor/ERBB1) and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription.[ PubMed:16460914 ]
Also Known As "ERBB1-ERBB4 signaling pathway" ; "ERBB4-EGFR signalling pathway" ; "HER1-HER4 signaling pathway"
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ERBB signaling pathway
 |__epidermal growth factor receptor signaling pathway__
 |__ERBB4 signaling pathway_____________________________|
                                                        ERBB4-EGFR signaling pathway
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Is a epidermal growth factor receptor signaling pathway
ERBB4 signaling pathway
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Synonyms
  • "ERBB1-ERBB4 signaling pathway" EXACT
    "ERBB4-EGFR signalling pathway" EXACT
    "HER1-HER4 signaling pathway" EXACT
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