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General Information
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| Term |
RIG-I signaling pathway |
ID (Ontology) |
GO:0039529 (Gene Ontology) |
| Definition |
The series of molecular signals initiated by the binding ssRNA or dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58). RIG-I detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines.[ PubMed:17328678 PubMed:19620789 PubMed:21435580 PubMed:25579795 ] |
| Also Known As |
"DDX58 signaling pathway" ; "retinoic acid inducible gene I signaling pathway" ; "RIG-I signalling pathway" (for all, see Synonyms field below) |
| Comment |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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No relevant records available
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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No relevant statements available
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Relationships
