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| Term | symbiont-mediated suppression of host PKR/eIFalpha signaling | ID (Ontology) | GO:0039580 (Gene Ontology) |
| Definition | A process in which a symbiont inhibits or disrupts host PKR (Protein Kinase regulated by RNA) signaling. PKR phosphorylates host targets such as the translation initiation factor eIF2alpha that inhibits protein synthesis as an antimicrobial response. Inhibition of host PKR signaling maintains the host ability to translate mRNA. The host is defined as the larger of the organisms involved in a symbiotic interaction.[ PubMed:15207627 ] | ||
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symbiont-mediated suppression of host defenses |__symbiont-mediated suppression of host-directed shutoff of host translation__ symbiont-mediated perturbation of host signal transduction pathway | |__symbiont-mediated suppression of host signal transduction pathway___________| symbiont-mediated suppression of host PKR/eIFalpha signaling |
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symbiont-mediated suppression of host signal transduction pathway symbiont-mediated suppression of host-directed shutoff of host translation |
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| VZ:554 | |||
