FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term symbiont-mediated-mediated suppression of host tetherin activity ID (Ontology) GO:0039587 (Gene Ontology)
Definition Any process in which a symbiont stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects.[ PubMed:22493439 ]
Also Known As "inhibition of host BST2/Tetherin by virus" ; "suppression by virus of host tetherin activity"
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  symbiont-mediated perturbation of host process
   |__symbiont-mediated perturbation of host defense response
       |__symbiont-mediated-mediated suppression of host tetherin activity
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Is a symbiont-mediated perturbation of host defense response
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Synonyms
  • "evasion of suppression of viral release by host via inhibition of host tetherin activity" NARROW
    "inhibition of host BST2/Tetherin by virus" EXACT
    "suppression by virus of host tetherin activity" EXACT
Secondary IDs
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VZ:665