FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term symbiont-mediated suppression of host gene expression ID (Ontology) GO:0039657 (Gene Ontology)
Definition A process in which a symbiont inhibits or disrupts expression of genes in its host. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Also Known As "host gene expression shutoff"
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  symbiont-mediated perturbation of host cellular process
   |__symbiont-mediated perturbation of host gene expression
       |__symbiont-mediated suppression of host gene expression
           |__symbiont-mediated suppression of host mRNA export from nucleus
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Is a symbiont-mediated perturbation of host gene expression
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Synonyms
  • "host gene expression shutoff" EXACT
    "host gene expression shutoff by virus" NARROW
    "suppression by virus of host gene expression" NARROW
Secondary IDs
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VZ:1582 "Host gene expression shutoff by virus"