FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term symbiont-mediated evasion of mRNA degradation by host via mRNA cap methylation ID (Ontology) GO:0039699 (Gene Ontology)
Definition An innate immune response evasion mechanism in which a symbiont methylates the 2'-O-ribose of the first or second transcribed nucleotide of its mRNAs. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs. This mechanism of immune evasion is used by viruses.[ PubMed:35215972 ]
Also Known As "evasion of mRNA degradation by host via mRNA cap methylation" ; "IFIT mRNA restriction evasion by virus"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
No relevant records available
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
Spanning Tree (Parents/Children)
Only view relationship:
  symbiont-mediated evasion of host innate immune response
   |__symbiont-mediated evasion of recognition by host innate immune effector
       |__symbiont-mediated evasion of mRNA degradation by host via mRNA cap methylation
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a symbiont-mediated evasion of recognition by host innate immune effector
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "evasion of mRNA degradation by host via mRNA cap methylation" EXACT
    "IFIT mRNA restriction evasion by virus" EXACT[ PubMed:35215972 ]
    "viral mRNA cap methylation" RELATED
Secondary IDs
hide External Crossreferences & Linkouts