FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term type 2 immune response ID (Ontology) GO:0042092 (Gene Ontology)
Definition An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.[ ISBN:0781735149 PubMed:18000958 PubMed:18007680 PubMed:20065995 PubMed:20200518 ]
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immune system process__
response to stimulus___|
                       immune response
                        |__type 2 immune response
                            |__regulation of type 2 immune response
                            |   |__negative regulation of type 2 immune response(+)
                            |   |__positive regulation of type 2 immune response(+)
                            |   |__regulation of T-helper 2 cell cytokine production(+)
                            |   |__regulation of T-helper 2 cell differentiation(+)
                            |__T-helper 2 cell cytokine production
                            |   |__regulation of T-helper 2 cell cytokine production(+)
                            |__T-helper 2 cell differentiation
                                |__regulation of T-helper 2 cell differentiation(+)
                                |__T-helper 2 cell lineage commitment
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Synonyms
  • "T-helper 2 type immune response" NARROW
    "Th2 immune response" NARROW
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